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ChemInform Abstract: A Novel Stereoselective Synthesis of (2Z)-2-Arylsulfanylallylic Alcohols (III) by Tin—Lithium Exchange of (E)-α-Stannylvinyl Sulfides (I).

✍ Scribed by Yaping Xu; Wenyan Hao; Dong Wang; Mingzhong Cai


Publisher
John Wiley and Sons
Year
2008
Weight
38 KB
Volume
39
Category
Article
ISSN
0931-7597

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A novel stereoselective synthesis of (2Z
✍ Yaping Xu; Wenyan Hao; Dong Wang; Mingzhong Cai 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB

## Abstract Tin–lithium exchange reaction of (__E__)‐α‐stannylvinyl sulfides **1** with __n__‐butyllithium gave (__Z__)‐α‐arylsulfanylvinyllithiums **2**, which reacted with aldehydes or ketones **3** to afford stereoselectively (2__Z__)‐2‐arylsulfanylallylic alcohols **4** in good to high yields.