ChemInform Abstract: A Novel Series of Matrix Metalloproteinase Inhibitors for the Treatment of Inflammatory Disorders.
β Scribed by A. D. BAXTER; J. BIRD; R. BHOGAL; T. MASSIL; K. J. MINTON; J. MONTANA; D. A. OWEN
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
A novel model to assess the in vivo bioactivity of matrix metalloproteinase (MMP) inhibitors is described. A solution containing the target enzyme, either stromelysin (MMP-3) or collagenase (MMP-1), was put inside dialysis tubing which was then implanted either intraperitoneally or subcutaneously in