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ChemInform Abstract: A Novel Bridged Nucleoside Bearing a Conformationally Switchable Sugar Moiety in Response to Redox Changes.

✍ Scribed by Takeshi Baba; Tetsuya Kodama; Kazuto Mori; Takeshi Imanishi; Satoshi Obika


Publisher
John Wiley and Sons
Year
2011
Weight
25 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

A novel nucleoside analogue (IV) with a disulfide bridge structure at the sugar moiety, which shows redox‐responsive reversibility of the sugar conformation due to the formation and scission of the disulfide bond, is designed and synthesized.