ChemInform Abstract: A Novel Base Promoted Reaction of Methyl 2-Isoxazoline-5-acetates to 5-(2-Oxoethyl)-3-isoxazolidinones.

✍ Scribed by K. EICHINGER; M. R. ROSTAMI; F. SIEDER

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 30 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199840121

✦ Synopsis

1998 isoxazole derivatives isoxazole derivatives R 0240 40 -121 A Novel Base Promoted Reaction of Methyl 2-Isoxazoline-5-acetates to 5-(2-Oxoethyl)-3-isoxazolidinones.

-The preparation of the title compounds (IV) by reaction of isoxazoline-5-acetates (III) with sodium hexanolate is reported. A reaction mechanism for this reaction involving an unusual C-O bond cleavage is proposed and discussed. -(EICHINGER, K.;