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ChemInform Abstract: A Novel and Regioselective Pyridine-Ring Formation by Lewis Acid-Induced Cyclization of 2-(N-Allylbenzylamino)-3-[2,2-bis(ethoxycarbonyl)vinyl]pyrido [1,2-a]pyrimidin-4(4H)-one.

✍ Scribed by M. NOGUCHI; H. YAMADA; T. SUNAGAWA


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


A Novel and Regioselective Pyridine-Ring Formation by Lewis Acid-Induced Cyclization of 2-(N-Allylbenzylamino)-3-[2,2bis(ethoxycarbonyl)vinyl]pyrido [1,2-a]pyrimidin-4(4H)-one.

-The title pyridine-ring formation is achieved via an intermediately obtained iminium betaine according to the "tert-amino effect". -(NOGUCHI, M.;


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