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ChemInform Abstract: A Novel Allylic Hydroxylation of Sterically Hindered Olefins by Fe—Porphyrin-Catalyzed mCPBA Oxidation.

✍ Scribed by Toshiro Konoike; Yoshitaka Araki; Yasuhiko Kanda


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


A Novel Allylic Hydroxylation of Sterically Hindered Olefins by Fe-Porphyrin-Catalyzed mCPBA Oxidation.

-Triterpenes such as (I) bearing a sterically hindered olefin readily undergo a novel allylic hydroxylation by MCPBA in the presence of iron(III) tetrakis(pentafluorophenyl)porphyrin chloride as catalyst. Sterically unhindered olefins [cf. (III), (V)] are converted to epoxides under these conditions. -(KONOIKE, TOSHIRO; ARAKI, YOSHI-