ChemInform Abstract: A New Synthesis of 8-Oxabicyclo[3.2.1]octan-2-one and Its Use for the Preparation of Cycloheptane Annulated Furans.
β Scribed by Henning Hopf; K. G. Abhilash
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Enantioselective Deprotonation of the 8-Oxabicyclo[3.2.1]octan-3-one: Synthesis of 8-Oxa-norcocaines and 8-Oxa-pseudonorcocaines. -Asymmetric deprotonation of the racemic ketone (I) using chiral lithium amides provides ready access to the non-racemic Ξ²-ketoesters (III), which can be easily transfor
## Synthesis of the Pseudoguaianolide and Guaianolide Skeleton by Cleavage of the Ether Bridge of 8-Oxabicyclo[3.2.1]octan-3-one Derivatives. -The ZrCl 4 -promoted cleavage of the ether bridge of title oxabicyclooctane (I) provides, depending on the reaction conditions used, various types of poly