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ChemInform Abstract: A New HPLC Chiral Stationary Phase for the Direct Resolution of Racemic Quinolone Antibacterials Containing a Primary Amino Group.

✍ Scribed by M. H. HYUN; J. S. JIN; W. LEE

Publisher: John Wiley and Sons
Year: 2010
Weight: 26 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199852307

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Abstract

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Two selectors derived from [(S)-1-(1-naphthyl)ethyl]amine and (S)-leucine have been chemically bonded to one another and the resulting chiral auxiliary linked covalently to silica gel, to produce a new chiral stationary phase (CSP) for the HPLC resolution of enantiomers. The CSP is able to separate