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ChemInform Abstract: A New Enantioselective Route to the Sceletium Alkaloids via a Cyclopentanone—Cyclohexenone Transformation.

✍ Scribed by Masato Hayashi; Tomohiro Unno; Michiyasu Takahashi; Kunio Ogasawara


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Enantioselective Sy
✍ Raymond E. Conrow; W. Dennis Dean; Paul W. Zinke; Michael E. Deason; Steven J. S 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

Enantioselective Synthesis of Brinzolamide (AL-4862), a New Topical Carbonic Anhydrase Inhibitor. The "DCAT Route" to Thiophenesulfonamides. -A facile large scale synthesis of the topical carbonic anhydrase inhibitors AL-4862 (IXa) and its side chain nor-homologue AL-4623A (IXb) starting from 3-ace