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ChemInform Abstract: A New Efficient Synthesis of 6-Nitroquipazine.

✍ Scribed by Byoung Se Lee; Byung Chul Lee; Jong-Gab Jun; Dae Yoon Chi

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

A New Efficient Synthesis of 6-Nitroquipazine.

-A new convenient and regioselective synthesis of 6-nitroquipazine (V), one of the most potent and selective antagonist of 5-hydroxyltryptamine transporter, from commercially available hydrocarbostyril (I) using a nitration/ chlorination/ aromatization/ aromatic substitution sequence is described. -(LEE, BYOUNG SE;

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