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ChemInform Abstract: A New Domino Reaction Based on [4 + 2]-Cycloadditions of Pyrido[1,2-a]pyrazines with Azadienophiles.

✍ Scribed by Thomas Billert; Rainer Beckert; Peer Fehling; Manfred Doering; Joerg Brandenburg; Helmar Goerls; Peter Langer

Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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1,2a)pyrazines. -An expedient one-pot synthesis of the title compounds, which are of interest as chemotherapeutics or as organic dyes, is presented. Mechanistical key steps in this synthesis are a (4 + 2) cycloaddition and a ring opening process followed by 1