ChemInform Abstract: A Modular Synthesis of Functionalized Pyridines Through Lewis Acid-Mediated and Microwave-Assisted Cycloadditions Between Azapyrylium Intermediates and Alkynes.

A Modular Synthesis of Functionalized Py

A Modular Synthesis of Functionalized Pyridines through Lewis-Acid-Mediated and Microwave-Assisted Cycloadditions between Azapyrylium Intermediates and Alkynes

✍ Igor Linder; Markus Gerhard; Luise Schefzig; Michal Andrä; Christoph Bentz; Hans 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 491 KB

## Abstract In this report we describe the synthesis of differentially functionalized pyridine derivatives **3** and the related 3‐bromo‐substituted pyridines **11**. Dissociation of 6__H__‐1,2‐oxazine precursors (**1a**, **1b**, **5**, **6**, or **12**) in situ, mediated by boron trifluoride–dieth