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ChemInform Abstract: A Highly Efficient Synthesis of Oligodeoxyribonucleotides Containing the 2′-Deoxyribonolactone Lesion.

✍ Scribed by Mitsuharu Kotera; Anne-Gaelle Bourdat; Eric Defrancq; Jean Lhomme


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
30
Category
Article
ISSN
0931-7597

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The 7-Nitroindole Nucleoside as a Photoc
✍ Mitsuharu Kotera; Yoann Roupioz; Eric Defrancq; Anne-Gaëlle Bourdat; Julian Garc 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB

On the basis of molecular modeling studies, the 7-nitroindole nucleoside 1 was selected as a suitable photochemical precursor for photochemical generation of the C1' deoxyribosyl radical under irradiation, which led to 2'-deoxyribonolactone. The nitroindole nucleoside derivatives 1 a and 1 b were pr