A general and efficient route to 6-methy
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Paul J. J. Colbon; Alison C. Foster; Melvyn E. Giles; Zakariya Patel; John T. Si
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Article
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2008
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Journal of Heterocyclic Chemistry
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English
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## Abstract magnified image We have developed a convenient twoโstage process for the synthesis of 6โmethylpyrazineโ2โylโamines from commercially available materials. The procedure involves the synthesis of (6โchloroโpyrazinโ2โyl)โacetic acid __via__ arylation of diethyl malonate and __in situ__ hy