ChemInform Abstract: A Flow Chemistry Route to 2-Phenyl-3-(1H-pyrrol-2-yl)propan-1-amines.

✍ Scribed by Mark Tarleton; Adam McCluskey

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 27 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201128106

✦ Synopsis

Abstract

Raney‐Ni catalyzed flow hydrogenation of α,β‐unsaturated nitriles in methanol provides the title compounds (II), whereas Pd‐C in acetone allows the selective reduction of the olefin double bond to give the saturated nitrile (III).