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ChemInform Abstract: A Facile Synthesis and Discovery of Highly Functionalized Tetrahydropyridines and Pyridines as Antimycobacterial Agents.

✍ Scribed by Suresh Kumar Raju; Michael Rajesh Stephen; Perumal Subbu; Banerjee Debjani; Yogeeswari Perumal; Sriram Dharmarajan

Publisher: John Wiley and Sons
Year: 2010
Weight: 48 KB
Volume: 41
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201045142

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✦ Synopsis

Abstract

A variety of novel highly functionalized tetrahydropyridine derivatives is synthesized via multicomponent reactions of arylsulfonylbutanoates (I) with aromatic aldehydes and ammonium acetate and transformed into corresponding aromatics upon dehydrogenation with DDQ.

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