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ChemInform Abstract: A Facile Direct anti-Selective Catalytic Asymmetric Mannich Reaction of Aldehydes with Preformed N-Boc and N-Cbz Imines.

✍ Scribed by Yong-Ming Chuan; Gui-Hua Chen; Jiu-Zhi Gao; Hui Zhang; Yun-Gui Peng

Publisher: John Wiley and Sons
Year: 2011
Weight: 37 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201128025

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✦ Synopsis

Abstract

The application of the chiral pyrrolidine based thiourea organocatalyst (PTU) produces the anti‐Mannich products in excellent yields as well as diastereo‐ and enantioselectivities.

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