Structure-based discovery of tipranavir
โ
Suvit Thaisrivongs; Joseph W. Strohbach
๐
Article
๐
1999
๐
Wiley (John Wiley & Sons)
๐
English
โ 167 KB
Efforts to develop therapeutically relevant HIV protease inhibitors as medicinal agents in confronting the AIDS crisis have been aided by the wealth of fundamental information acquired during related drug discovery campaigns against other aspartyl proteases. This knowledge base was brought to full f