ChemInform Abstract: A Convenient Synthesis of Thiirene 1-Oxides.
β Scribed by Juzo Nakayama; Kenta Takahashi; Yoshiaki Sugihara; Akihiko Ishii
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
In contrast to carbonyl compounds, the 17O chemical shifts of aryl sulfoxides are deshielded by electron donor substituents and show only slight sensitivity. In a thiirene-1-oxide the e β ect of interaction between the CxC and SΓO groups is also small. 1998 John Wiley & Sons, Ltd.
A practical and efficient approach for the synthesis of the title compound (IX), a naturally occurring phenylheptane derivative, involving the Friedel-Crafts acylation of benzene with glutaric anhydride as source of the 1,5-dione functionality is accomplished.