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ChemInform Abstract: A Convenient Synthesis of (S)-3-Methyladipic Acid.

✍ Scribed by J. W. LEAHY; B. HUANG


Book ID
112021360
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
26
Category
Article
ISSN
0931-7597

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## Abstract Monoamination of dibromopyridines (I) and (VIII) followed by carbonylation and subsequent hydrolysis of methyl esters (VI) and (X) furnish (alkylamino)pyridinecarboxylic acids (VII) and (XI) in satisfactory to good yields, though the 3,5‐dibromopyridine (VIII) reacts more slowly.