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ChemInform Abstract: A Convenient Synthesis of 1,3-Disubstituted-4- (1′,3′-dithiolane/dithiane-2′-ylidene)-2-pyrazolin-5-ones.

✍ Scribed by V. K. Ahluwalia; Suman Dudeja

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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ChemInform Abstract: Stereoselective Syn
ChemInform Abstract: Stereoselective Synthesis of 1,3-Disubstituted Hexahydro-1,4-diazepin- 2-ones.
✍ A. POHLMANN; D. GUILLAUME; J.-C. QUIRION; H.-P. HUSSON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Stereoselective Synthesis of 1,3-Disubstituted Hexahydro-1,4diazepin-2-ones. -A fast and facile asymmetric synthesis of the title compounds (VI), a kind of constrained peptides, involving the diastereoselective alkylation of optically pure hydroxylactam (IV) as the key step is described.