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ChemInform Abstract: A Concise Synthesis of a Very Late Antigen-4 Antagonist trans-4-[1-[ [2,5-Dichloro-4-(1-methyl-3-indolylcarboxyamide)phenyl]acetyl] -(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid (V) via Reductive Etherification.

โœ Scribed by Chiba, Jun; Muro, Fumihito; Setoguchi, Masaki; Machinaga, Nobuo

Book ID
118755757
Publisher
John Wiley and Sons
Year
2012
Weight
31 KB
Volume
43
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Novel Synthetic A
ChemInform Abstract: A Novel Synthetic Approach to Very Late Antigen-4 Antagonist trans-4-[1-[ [2,5-Dichloro-4-(1-methyl-3-indolylcarboxyamide)phenyl]acetyl] -(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid (VIII) via tert-Butyl trans-[(4S)-Methoxy-(2S)-pyrrolidinylmethoxy] Cyclohexanecarboxylate (VI) as a Key Intermediate.
โœ Jun Chiba; Nobuo Machinaga ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 1 views

A Novel Synthetic Approach to Very Late Antigen-4 Antagonist trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxyamide)phenyl]acetyl]--(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid (VIII) via tert-Butyl trans-[(4S)-Methoxy-(2S)-pyrrolidinylmethoxy] Cyclohexanecarboxylate (VI) as