ChemInform Abstract: 9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno [1,2-e]pyrazin-4-one-2-carbocylic Acid (RPR117824): Selective Anticonvulsive and Neuroprotective AMPA Antagonist.

ChemInform Abstract: Synthesis of Antico

ChemInform Abstract: Synthesis of Anticonvulsive AMPA Antagonists: 4-Oxo-10-substituted-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic Acid Derivatives.

✍ Serge Mignani; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Synthesis and pharmacological properties

Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist

✍ Serge Mignani; Jean-Claude Aloup; Michel Barreau; Jean Charles Blanchard; Georg 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 1 views

The excessive release of glutamate, a potent excitatory neurotransmitter, is thought to play an important role in a variety of acute and chronic neurological disorders. Consequently, excitatory amino acid antagonists may have an important therapeutic potential in the treatment of these diseases. Glu

ChemInform Abstract: 8-Methylureido-4,5-

ChemInform Abstract: 8-Methylureido-4,5-dihydro-4-oxo-10H-imidazo[1,2-a]indeno [1,2-e]pyrazines: Highly Potent in vivo AMPA Antagonists.

✍ Serge Mignani; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Synthesis and Poten

ChemInform Abstract: Synthesis and Potent Anticonvulsant Activities of 4-Oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8- and -9-carboxylic (Acetic) Acid AMPA Antagonists.

✍ Serge Mignani 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

ChemInform Abstract: 4,10-Dihydro-4-oxo-

ChemInform Abstract: 4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic Acid Derivatives: Highly Potent and Selective AMPA Receptors Antagonists with in vivo Activity.

✍ Serge Mignani; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Bioisosteres of 9-C

ChemInform Abstract: Bioisosteres of 9-Carboxymethyl-4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic Acid Derivatives. Progress Towards Selective, Potent in vivo AMPA Antagonists with Longer Durations of Action.

✍ Serge Mignani; et al. et al. 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 32 KB