ChemInform Abstract: 7α,11β-Disubstituted Estrogens: Probes for the Shape of the Ligand Binding Pocket in the Estrogen Receptor.

✍ Scribed by R. TEDESCO; J. A. KATZENELLENBOGEN; E. NAPOLITANO

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 38 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199810215

✦ Synopsis

7α,11β-Disubstituted Estrogens: Probes for the Shape of the Ligand Binding Pocket in the Estrogen Receptor.

-Title compounds, e.g. (IV) and (XII), are prepared to explore the size and shape of specific regions of the ligand binding pocket of the estrogen receptor. -(TEDESCO, R.;