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ChemInform Abstract: 7-Halogenated 7-Deaza-2′-deoxyinosines.

✍ Scribed by Natalya Ramzaeva; Cathrin Mittelbach; Frank Seela

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

43 -212

7-Halogenated 7-Deaza-2'-deoxyinosines. -Title compounds (VI) are prepared following two different approaches as potential substitutes of regular 2'-deoxynucleosides within DNA fragments.

-(RAMZAEVA, NATALYA;

📜 SIMILAR VOLUMES

7-Halogenated 7-Deaza-2′-deoxyxanthine 2
7-Halogenated 7-Deaza-2′-deoxyxanthine 2′-Deoxyribonucleosides
✍ Frank Seela; Khalil Shaikh 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 117 KB

## Abstract The synthesis of the 7‐halogenated derivatives **1b** (7‐bromo) and **1c** (7‐iodo) of 7‐deaza‐2′‐deoxyxanthosine (**1a**) is described. A partial Br→I exchange was observed when the demethylation of 6‐methoxy precursor compound **4b** was performed with Me~3~SiCl/NaI. This reaction is