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ChemInform Abstract: 5′-Alkyl-benzothiadiazides: A New Subgroup of AMPA Receptor Modulators with Improved Affinity.

✍ Scribed by Dean Phillips; Jennifer Sonnenberg; Amy C. Arai; Rishi Vaswani; Peter O. Krutzik; Thomas Kleisli; Markus Kessler; Richard Granger; Gary Lynch; A. Richard Chamberlin


Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
33
Category
Article
ISSN
0931-7597

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Synthesis of New (Benzimidazolyl)piperazines with Affinity for the 5-HT 1A Receptor via Pd(0) Amination of Bromobenzimidazoles. -Compounds (IIIa), (IIIb), (VI) and (IVa) are screened for their in vitro affinities at 5-HT 1A receptors by radioligand binding assays. (VI