✦ LIBER ✦
ChemInform Abstract: 2,2-Dicyanovinyl as a Nonaromatic Aryl Bioisostere: Synthesis, Binding Experiments, and SAR Studies of Highly Selective Dopamine D4 Receptor Ligands.
✍ Scribed by Christian Haubmann; Harald Huebner; Peter Gmeiner
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
2,2-Dicyanovinyl as a Nonaromatic Aryl Bioisostere: Synthesis, Binding Experiments, and SAR Studies of Highly Selective Dopamine D4 Receptor Ligands. -Title compounds of type (I) are tested for their dopamine receptor binding activity. Both types of 4-or 5-substituted compounds show selective dopamine D 4 receptor affinity. -(HAUBMANN,