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ChemInform Abstract: 2′-Spirocyclopropyl-carbocyclic Nucleosides as a Novel Scaffold for Potent anti-HCV Agents.

✍ Scribed by Hua Li; Jin Cheol Yoo; Joon Hee Hong

Book ID: 102062963
Publisher: John Wiley and Sons
Year: 2011
Weight: 40 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201138194

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✦ Synopsis

Abstract

Carbocyclic nucleoside analogues such as (XI) are prepared via a ring‐closing metathesis of intermediate (III) and spirocyclopropanation of enone (V) as key steps.

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