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ChemInform Abstract: 2′-Deoxy-2′-α-fluoro-2′-β-C-methyl 3′,5′-Cyclic Phosphate Nucleotide Prodrug Analogues as Inhibitors of HCV NS5B Polymerase: Discovery of PSI-352938.

✍ Scribed by P. Ganapati Reddy; et al. et al.


Publisher
John Wiley and Sons
Year
2011
Weight
23 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The title compound (I) exhibits 100‐fold higher potency than the parent nucleoside.