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ChemInform Abstract: 2-Aminopurine Peptide Nucleic Acids (2-apPNA): Intrinsic Fluorescent PNA Analogues for Probing PNA—DNA Interaction Dynamics.

✍ Scribed by B. P. GANGAMANI; V. A. KUMAR; K. N. GANESH


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


2-Aminopurine Peptide Nucleic Acids (2-apPNA): Intrinsic Fluorescent PNA Analogues for Probing PNA-DNA Interaction Dynamics. -Monomer (II) (no yield given) is used for incorporation into PNA-oligomer in place of non-fluorescent adenine. Kinetics of the PNA-DNA hybridization process is examined by investigating the fluorescence of the mentioned oligomer. -(GANGAMANI, B.