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ChemInform Abstract: 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) Catalyzed Regiospecific and Diastereoselective Reaction of Chiral N-(tert-Butanesulfinyl)ketimines and α,β-Unsaturated Trifluoromethyl Ketones.

✍ Scribed by Fan Zhang; Zhenjiang Liu; Jintao Liu


Book ID
112043038
Publisher
John Wiley and Sons
Year
2012
Weight
31 KB
Volume
43
Category
Article
ISSN
0931-7597

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1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)
✍ Fan Zhang; Zhenjiang Liu; Jintao Liu 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB

## Abstract The reaction of chiral __N__‐(__tert__‐butanesulfinyl)ketimines and __α__,__β__‐unsaturated trifluoromethyl ketones catalyzed by DBU was achieved under mild conditions. 1,2‐Addition products, precursors of chiral trifluoromethylated 1,3‐amino alcohols, were obtained diastereoselectively