ChemInform Abstract: 1,4-Addition of Organolithium Compounds to 6-Ethoxy-3-phenyl-6H-1,2-oxazine.

✍ Scribed by Reinhold Zimmer; Florian Hiller; Hans-Ulrich Reissig

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199922162

✦ Synopsis

The trans-selective addition of alkyl lithiums to oxazines generates 4-lithiated 1,2-oxazines, which are trapped with electrophiles to give 5,6-trans-substituted oxazines as major products. -(ZIMMER, REINHOLD;