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ChemInform Abstract: 1,3-Cycloadditions to Highly Substituted, Strained Double Bonds: Spiro- β-lactams from α-Methylidene-β-lactams by Reactions with Diphenylnitrilimine, Acetonitrile Oxide, Nitrones, and Diazomethane.

✍ Scribed by A. STRAUSS; H.-H. OTTO

Publisher: John Wiley and Sons
Year: 2010
Weight: 35 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199749129

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✦ Synopsis

Spiroβ-lactams from α-Methylidene-β-lactams by Reactions with Diphenylnitrilimine, Acetonitrile Oxide, Nitrones, and Diazomethane.

-Starting with the lactams (I) some β-lactams with a spiro(3,4) structure are synthesized by the title 1,3-cycloadditions. In the case of (Ia) the reaction gives the same results by using the pure (E)-or ( Z)-isomer or a mixture. All reaction products are relatively unstable, especially in solution; the cycloreversion is highly favored. -(STRAUSS, A.

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✍ S. GUERTLER; S. RUF; M. JOHNER; H.-H. OTTO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views