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ChemInform Abstract: 1,2-Disubstituted 4-Quinolones via Copper-Catalyzed Cyclization of 1-(2-Halophenyl)-2-en-3-amin-1-ones.

✍ Scribed by Roberta Bernini; Sandro Cacchi; Giancarlo Fabrizi; Alessio Sferrazza


Publisher
John Wiley and Sons
Year
2009
Weight
26 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Stereoselective Syn
✍ A. POHLMANN; D. GUILLAUME; J.-C. QUIRION; H.-P. HUSSON πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 29 KB πŸ‘ 1 views

Stereoselective Synthesis of 1,3-Disubstituted Hexahydro-1,4diazepin-2-ones. -A fast and facile asymmetric synthesis of the title compounds (VI), a kind of constrained peptides, involving the diastereoselective alkylation of optically pure hydroxylactam (IV) as the key step is described.