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ChemInform Abstract: 11,12,4′′-Tri-O-methylazithromycin Monohydrate.

✍ Scribed by B. KAMENAR; N. K. HULITA; I. VICKOVIC; G. KOBREHEL; G. LAZAREVSKI


Book ID
101842481
Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


The X-ray structure analysis of the title compound (I), an O-methylated derivative of the 15-membered semisynthetic azalide antibiotic azithromycin, is undertaken. The introduced methyl groups do not essentially affect the molecular conformation. Both sugars are in chair conformations. The water molecule is hydrogen bonded to both the lactone and cladinose rings. -(KAMENAR, B.; HULITA, N. K.;


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