✦ LIBER ✦
ChemInform Abstract: 1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a Potent, Selective, and Orally Available Soluble Epoxide Hydrolase Inhibitor with Efficacy in Rodent Models of Hypertension and Dysglycemia.
✍ Scribed by Sampath-Kumar Anandan; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 19 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
The synthesis of the clinical candidate (I) and its analogues is achieved via a library approach allowing the facile preparation of various left hand side and right hand side combinations around the piperidinyl urea nucleus.