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Chemiluminescence associated with the oxidative metabolism of salicylic acid in rat liver microsomes

✍ Scribed by Hirokazu Doi; Hiromi Iwasaki; Yasuhiro Masubuchi; Ryuichiro Nishigaki; Toshiharu Horie


Book ID
114008851
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
153 KB
Volume
140
Category
Article
ISSN
0009-2797

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Hepatic metabolism of salicylic acid was studied using a single-pass liver perfusion technique. Livers obtained from male, Sprague-Dawley rats (200-300 g) were perfused with Krebs-Henseleit bicarbonate buffer containing the drug (50-100 micrograms/mL) and glycine (0.5 or 5 mM) or glucose (5.5 mM) or