Chemically accurate protein structures: Validation of protein NMR structures by comparison of measured and predicted pKavalues
β Scribed by N. Powers; Jan H. Jensen
- Publisher
- Springer Netherlands
- Year
- 2006
- Tongue
- English
- Weight
- 458 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0925-2738
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Since it was observed that the structural class of a protein is related to its amino acid composition, various methods based on amino acid composition have been proposed to predict protein structural classes. Though those methods are effective to some degree, their predictive quality is confined bec
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This study deals with structure class/secondary structure prediction of proteins using hidden Markov models (HMMs). With the proposed method, prediction is performed using HMMs designed so as to represent hierarchicality and periodicity of protein structural features. Secondary structures (partial t