Novel Chemical Transformations of Tenoxi
✍
Kristóf Kóczián; József Kökösi; Károly Mazák; Béla Noszál
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
German
⚖ 107 KB
👁 1 views
Both N-and O-substituted derivatives of the anti-inflammatory drug tenoxicam ( 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e] [1,2]thiazine-3-carboxamide 1,1-dioxide; 1) were synthesized, and various chemical transformations were investigated. Both selective hydrolysis and reaction of 1'-N-met