Chemical synthesis of TASP arrays and their application in protein design
✍ Scribed by Wolfgang Haehnel
- Book ID
- 111600773
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 466 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1381-1991
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## Abstract The design, total chemical synthesis, and immunological properties of a four‐__α__‐helix bundle template‐assembled synthetic protein (TASP) mimicking some of the structural features of the major histocompatibility complex (MHC) class I is described. In a first approach, the native seque
## Abstract Two new ^35^S reagents were developed to radiolabel proteins. The first reagent, __N__‐succinimidyl‐4‐(methane [^35^S]sulfonylamino‐methyl)‐benzoate (SMSB), acylates the ε‐amino group of lysine residues in proteins. The second reagent, 4‐(methane [^35^S]sulfonylamino‐methyl)‐phenylpropy