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Chemical Synthesis of a Skeleton Structure of Sperm CD52—A GPI-Anchored Glycopeptide

✍ Scribed by Ning Shao; Jie Xue; Zhongwu Guo

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
232 KB
Volume
116
Category
Article
ISSN
0044-8249

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✍ Dr. Srinivas Burgula; Dr. Benjamin M. Swarts; Prof. Dr. Zhongwu Guo 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 352 KB 👁 1 views

## Abstract The first total synthesis of a glycosylphosphatidylinositol (GPI) anchor bearing a polyunsaturated arachidonoyl fatty acid is reported. This lipid is found in mammalian GPIs that do not undergo lipid remodeling, a process that has important implications in the localization and function