Chemical sulfation of preparations of chondroitin 4- and 6-sulfate, and dermatan sulfate. Preparation of chondroitin sulfate E-like materials from chondroitin 4-sulfate
β Scribed by Kinzo Nagasawa; Hideki Uchiyama; Norie Wajima
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 868 KB
- Volume
- 158
- Category
- Article
- ISSN
- 0008-6215
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π SIMILAR VOLUMES
High-voltage capillary zone electrophoresis (CZE) has been used for the first time in the analysis of non-, mono-, di-, and trisulfated disaccharides derived from chondroitin sulfate, dermatan sulfate, and hyaluronic acid. These glycosaminoglycans are first depolymerized using polysaccharide lyases.
Chondroitin and dermatan sulfates are families of structurally complex, sulfated, linear polysaccharides called glycosaminoglycans (GAGs) with alternating uronic acid and N-acetylated D-galactosamine residues [ 1] (Scheme 1). Chondroitin sulfate A (1A) consists of unsulfated D-glucuronic acid 1--\*