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Chemical modification of gene silencing oligonucleotides for drug discovery and development

โœ Scribed by Xiaolan Chen; Nancy Dudgeon; Long Shen; Jui H. Wang

Book ID
114385046
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
162 KB
Volume
10
Category
Article
ISSN
1359-6446

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## Abstract A fundamental goal of chemical proteomics is to identify target proteins for bioactive small molecules and then apply them to drug discovery and development as valid and drugable targets. Here, we introduce integrated technologies for the rapid identification of target proteins, methodo