New technologies for chemical genetics
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Leslie A. Walling; Noรซl R. Peters; Edward J. Horn; Randall W. King
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Article
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2001
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John Wiley and Sons
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English
โ 290 KB
Chemical genetics, in which small molecules are used in lieu of mutations to study biological processes, requires large and diverse chemical libraries to speciยฎcally perturb different biological pathways. Here we describe a suite of technologies that enable chemical libraries prepared by split-pool