Contents......Page 5
Preface......Page 7
Acknowledgements......Page 8
1 Food, Nutrition and Food Safety: An Introduction......Page 9
2 The Food Production and Processing Chain......Page 12
3 Unwanted Chemical Substances......Page 23
4 The Production and Processing Chain in Food Safety......Page 31
5 Introduction to ADME (Absorption, Distribution, Metabolism and Excretion)......Page 36
6 Absorption and Distribution of Chemical Compounds......Page 39
7 Metabolism of Chemical Compounds......Page 48
8 Excretion of Chemical Compounds and Their Metabolites......Page 57
9 Toxicokinetics......Page 61
10 Toxicodynamics......Page 69
11 An Introduction to the History of Regulation and Control Worldwide: (International Institutions in Risk Assessment and Safety Regulation)......Page 76
12 The EU with EFSA and EMEA......Page 83
13 Safety Assessment Methods in the Laboratory: Toxicity Testing......Page 88
14 In vitro Methods......Page 99
15 Naturally Inherent Plant Toxicants: Introduction and Non-glycosidic Compounds......Page 105
16 Naturally Inherent Plant Toxicants: Glycosides......Page 119
17 Naturally Inherent Toxins: Mushrooms, Algae (Marine Biotoxins) and Animals......Page 136
18 An Introduction to Food Contaminants and About Metals, Metalloids and Other Elements......Page 140
19 Mycotoxins......Page 159
20 Pesticides and Persistent Organic Pollutants......Page 172
21 Contaminants From Processing Machinery and Food Contact Materials......Page 199
22 Toxic Compounds Formed During Processing or Improper Storage......Page 204
23 Veterinary Drugs and Contaminant Overall Conclusion......Page 224
24 Food Additives and Flavourings, Etc.......Page 227
25 Food Allergies and Intolerances......Page 246
26 Analytical Chemistry in Food Safety......Page 249
27 Risk Analysis......Page 268
28 Food Safety (Quality) Assurance and Certification of Production......Page 273
29 GMOs and Food......Page 277
30 Cases......Page 281
A......Page 285
C......Page 286
E......Page 287
F......Page 288
I......Page 289
M......Page 290
N......Page 291
P......Page 292
S......Page 293
T......Page 294
Z......Page 295