Chemical equivalence of two polyetherpolyurethane foams as a vehicle for povidone—iodine solution: Kinetic model for the loss of available iodine
✍ Scribed by David J. Mazzo; Thomas Bujak; Robert Martin
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 406 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0731-7085
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✦ Synopsis
The loss of available iodine from povidone-iodine solution stored in contact with two different polyetherpolyurethane foams was monitored as a function of time and temperature. Statistical evaluation of the results for the four temperatures studied [ambient (25 degrees), 30, 45 and 55 degrees C] indicated the chemical equivalence of the two foams as storage and delivery systems for povidone-iodine solution in terms of solution stability. In addition, application of a first-order kinetic model to the data produced an acceptable fit. An Arrhenius-type evaluation of the resulting rate constants yielded a linear relationship which was shown to be useful for predicting loss of available iodine under ambient temperature conditions of storage.