Chemical investigation of drug-like comp
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Trong D. Tran; Ngoc B. Pham; Gregory Fechner; Ronald J. Quinn
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Article
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2010
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Elsevier Science
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English
β 283 KB
Two of the four parameters in the 'rule of five', molecular weight and log P, which can be detected and predicted by mass spectrometry and compound retention on reversed-phase HPLC, were used as guidelines in natural product isolation. A new aporphine alkaloid, (6aR)-normecambroline (1), was isolate