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Chemical Constituents of the Endophytic Fungal Strain Phomopsis sp. NXZ-05 of Camptotheca acuminata

✍ Scribed by Qifang Tan; Xuefen Yan; Xiang Lin; Yaojian Huang; Zhonghui Zheng; Siyang Song; Chunhua Lu; Yuemao Shen


Publisher
John Wiley and Sons
Year
2007
Tongue
German
Weight
81 KB
Volume
90
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

From the endophytic fungal strain Phomopsis sp. NXZ‐05 of Camptotheca acuminata Decne. (Nyssaceae), six new compounds were isolated, including the ten‐membered macrolides 14 and their (known) parent compound multiplolide A (7), as well as a new unsaturated fatty acid, (4__E__)‐6,7,9‐trihydroxydec‐4‐enoic acid (5) and its methyl ester 6. Their structures were elucidated by spectroscopic and mass‐spectrometric analyses, including 1D‐ and 2D‐NMR experiments and HR‐ESI‐MS, and their biological activities were elucidated.