✦ LIBER ✦
Chemical constituents of gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs
✍ Scribed by S. Ghosal; K. Biswas; R. K. Chaudhuri
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 217 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
✦ Synopsis
Anti-Mycobacterium tuberculosis H37 RV data are presented for the individual xanthones of Canscora decussata Schult and Swertia purpurascens Wall (Gentianaceae); a few, from the former species, showed significant activity. Additionally, sturcture--activity relationships of these compounds are evaluated on the basis of the minimum inhibitory concentration data of 18 naturally occurring xanthones bearing 1,3,5- 1,3,5,6-, 1,3,6,7-, 1,3,5,8-, 1,3,5,6,7-, and 1,3.6,7,8-oxygenated patterns and six synthetic analogs.