Title compound 1 was synthesized by a published route which had to be modified (seven steps from readily obtainable starting materials). Characterization of 1 was achieved by spectroscopic means (FAB-MS, ' H-NMR, including 2D-COSY). Furthermore, commercially available reference material purchased fo
Chemical combination of 6-deoxy-6-mycoloylamino-α,α-trehalose and N-acetyl-6-O-(aminoacyl)muramoyl dipeptide
✍ Scribed by Hideharu Ishida; Yuji Ogawa; Yasuyuki Imai; Makoto Kiso; Akira Hasegawa; Takuma Sakurai; Ichiro Azuma
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 684 KB
- Volume
- 194
- Category
- Article
- ISSN
- 0008-6215
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✦ Synopsis
6-Deoxy-6-mycoloylamino-a,a-trehalose, a biologically active derivative of 6,6'-di-0-mycoloyl-a,a-trehalose (TDM), andN-acetyl-6-O-(aminoacyl)-muramoyl dipeptide (MDP) were joined chemically by a succinic acid unit. The compounds synthesized showed activities that are characteristic of both TDM and MDP.
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